Mass Effect 2 has been known as an Xbox360 and PC game, but Bioware hasn't denied the possibility that the franchise may come to PS3. When CVG asked Bioware why they haven’t brought the series to PS3 yet, Muzyka stated the following:
“I think a more accurate way to frame it is to say we’ve announced we’re developing Mass Effect for 360 and PC. Right from the beginning we said we wanted to deliver Mass Effect on the 360. Right now all we’ve announced is we’re working on 360 and PC.”
“We haven’t announced anything on that front.”
Maybe Muzyka is holding off giving a definite no, because they are actually considering bringing the franchise to PS3.